Principal Product Manager, Clinical Platform

Twin Health 

At Twin Health, we empower people to improve and prevent chronic metabolic diseases, like type 2 diabetes and obesity, with a new standard of care. Twin Health is the only company applying AI Digital Twin technology exclusively toward metabolic health. 

We start by building a dynamic model of each person’s metabolism — drawing on thousands of data points from CGMs, smartwatches, and meal logs — that maps their personal path to better health. Guided by a dedicated clinical care team, our members have lowered their A1C below the diabetes range, achieved lasting weight loss, and reduced or even eliminated medications, all while living healthier, happier lives.

Working here 

Our team at Twin Health is passionate, talented, and united by a shared purpose: to improve the metabolic health and happiness of our members. We believe in empowering every Twin to make a meaningful impact for our members, our clients, and each other, while enjoying a supportive, collaborative work environment.

Twin has been recognized not only for our innovation but also for our culture, including: Innovator of the Year by the Employer Health Innovation Roundtable (EHIR), selected to CB Insights’ Digital Health 150, and named one of Newsweek’s Top Most Loved Workplace® .

With more than $100 million raised in recent funding, including a $53 million Series E round in 2025 led by Maj Invest, and a $50 million investment in 2023 led by Temasek, Twin is scaling rapidly across the U.S. and globally. Backed by leading venture firms like ICONIQ Growth, Sequoia, Sofina, Temasek, and Peak XV, we are building the most impactful digital health company in the world.

Join us as we reinvent the standard of care in metabolic health.

Opportunity 

We are looking for a Principal Product Manager to lead the development of Twin’s clinical platform, which powers the day-to-day workflows of physicians, health coaches, and other care team members. This platform is critical to enabling our clinical staff to deliver personalized, high-quality care to Twin’s members at scale. In this role, you will drive the creation of AI-powered tools, clinical workflows, and decision support features that help care teams work more efficiently, stay informed, and focus on what matters most: improving patient outcomes. 

You’ll work closely with design, engineering, data science, and clinical stakeholders to identify high-impact opportunities, prioritize solutions that meet real-world clinical needs, and ensure strong alignment across teams. This is an ideal opportunity for a strategic, user-centered product leader passionate about transforming healthcare through technology.

 Responsibilities 

• Own the strategy, roadmap, and execution for Twin’s clinical platform, enabling physicians, health coaches, and care team members to deliver effective, personalized care. 
• Design and deliver AI-powered features and intelligent workflows that support clinical decision-making, optimize care coordination, and improve efficiency across the care team.
• Collaborate closely with clinical stakeholders to deeply understand user needs, pain points, and operational workflows. 
• Translate clinical requirements into detailed product specifications, user stories, and Jira tickets for implementation. 
• Partner with Product Design to create intuitive, role-specific user experiences that integrate seamlessly into clinical routines. 
• Lead cross-functional agile teams including engineering, design, data science, and QA through all stages of the product lifecycle, from ideation to launch and iteration. 
• Define and track success metrics to measure impact on clinical performance, care quality, and patient outcomes. 
• Work closely with AI/ML teams to ensure technical solutions are interpretable, clinically safe, and effectively integrated into workflows. 
• Align with executive leadership and cross-functional partners to ensure product direction supports company strategy and clinical goals.

Qualifications

• 8+ years of product management experience, ideally in healthcare technology, clinical platforms.
• Experience designing and launching products for care teams, including physicians, coaches, nurses, or other allied health professionals. 
• Proven ability to build complex workflow tools and AI-integrated features that support high-stakes decision-making in regulated environments. 
• Strong understanding of clinical operations, healthcare delivery models, and the needs of multidisciplinary care teams. 
• Demonstrated ability to lead agile teams and manage the product development lifecycle end to end. 
• Strategic thinker with excellent execution skills capable of balancing long-term vision with short-term priorities. 
• Analytical mindset with the ability to use data to inform decisions, generate insights, and continuously improve product performance. 
• Excellent collaboration and communication skills, with a proven track record of aligning diverse stakeholders. 
• Experience with Electronic Medical Record (EMR) systems, clinical documentation tools, or care coordination platforms is a strong plus.

Compensation and Benefits  

The compensation range for this position is $180,000-$210,000 annually. 

Twin has an ambitious vision to empower people to live healthier and happier lives, and to achieve this purpose, we need the very best people to enhance our cutting-edge technology and medical science, deliver the best possible care, and turn our passion into value for our members, partners and investors. We are committed to delivering an outstanding culture and experience for every Twin employee through a company based on the values of passion, talent, and trust. We offer comprehensive benefits and perks in line with these principles, as well as a high level of flexibility for every Twin

• A competitive compensation package in line with leading technology companies
• A remote and accomplished global team
• Opportunity for equity participation 
• Unlimited vacation with manager approval
• 16 weeks of 100% paid parental leave for delivering parents; 8 weeks of 100% paid parental leave for non-delivering parents
• 100% Employer-sponsored healthcare, dental, and vision for you, and 80% coverage for your family; Health Savings Account and Flexible Spending Account options
• 401k retirement savings plan